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Contralateral Prophylactic Mastectomy

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What Contralateral Prophylactic Mastectomy Means

Contralateral prophylactic mastectomy (CPM) is surgery to remove the healthy breast in a person who has or had breast cancer in the other breast. The word "contralateral" means the opposite side of the body, and "prophylactic" means preventive. This surgery is done to lower the chance of developing a new breast cancer in the healthy breast. It involves removing all or most breast tissue from that side, but some breast tissue may remain, so the risk is lowered but not completely eliminated.

Why CPM Can Matter in Cancer Care

CPM is most often considered by people at very high risk of breast cancer, such as those with inherited gene changes like BRCA1 or BRCA2. For these individuals, CPM can significantly reduce the chance of developing cancer in the healthy breast. However, for people with average or low risk, the chance of cancer in the other breast is small, so CPM is usually not recommended. The surgery is a major decision because it involves risks, recovery time, and possible complications.

What Patients Might Experience and Hear

When discussing CPM, patients may hear about different types of mastectomy, such as total mastectomy (removing the nipple and areola) or nipple-sparing mastectomy, which can affect the breast’s appearance after surgery. Doctors will talk about the benefits of lowering cancer risk and the possible side effects or complications. Patients may also discuss breast reconstruction options. It is normal to have many questions about how CPM might affect quality of life and recovery.

Common Questions to Ask Your Care Team

If you are considering CPM, it is helpful to ask about your personal risk of cancer in the other breast, how much CPM might reduce that risk, what the surgery involves, and what recovery looks like. You can also ask about alternatives like increased screening or medications that lower risk. Talking with a genetic counselor or breast specialist can help you understand your options and make a decision that fits your health needs and personal values.

Understanding Limits and Next Steps

It is important to know that CPM does not guarantee that breast cancer will never develop in the healthy breast because some breast tissue may remain. CPM may also increase the risk of surgical complications and could delay treatment for the known cancer. This surgery is not recommended for everyone with breast cancer and is usually reserved for those at high risk. This information is educational and does not replace personalized medical advice. The best next step is to have open conversations with your healthcare team to understand your individual risk and treatment options fully.

Sources

Public source information used for this glossary entry includes: