Recent systematic review discussing temperature-dependent effects of induced hyperthermia on immune activation, DNA repair/genomic instability, treatment sensitivity, thermotolerance, and biomarkers.
Fever Therapy
Controlled therapeutic heating, including fever-range whole-body hyperthermia, local/regional hyperthermia, and related pyrogen-history approaches studied or used as adjuncts in cancer care. Fever Therapy is recorded here as the cancer-care family of controlled heat and fever-range approaches: local hyperthermia, regional hyperthermia, whole-body or fever-range whole-body hyperthermia, thermal ablation, HIPEC-style heated perfusion, and older pyrogen/immunotherapy traditions such as Coley's toxins.
Medical encyclopedia entry noting hyperthermia is usually combined with radiation or chemotherapy and is studied across multiple cancers.
NCI overview of local, regional, and whole-body hyperthermia, cancers studied, adjunctive use with radiation/chemotherapy, availability, and side effects.
ACS patient guide describing local, regional, and whole-body hyperthermia, its role with other cancer treatments, risks, and experimental status.
Systematic review of complementary medical hyperthermia methods; found heterogeneous and methodologically limited evidence and no reliable survival or quality-of-life evidence for alternative whole-body or electro-hyperthermia approaches.
Chapter focused on fever-range whole-body hyperthermia, water-filtered infrared-A irradiation, immunotherapy-era rationale, and limitations of the clinical evidence.
Clinical overview explaining hyperthermia, local/regional/whole-body methods, and how heat may weaken cancer cells or improve chemo/radiation response.
Historical and immunologic discussion of fever, pyrogens, Coley's toxins, BCG, OK-432, and related tumor-regression literature.