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Overview

This video, presented by Dr. Jill O'Donnell-Tormey, CEO and Director of Scientific Affairs at the Cancer Research Institute, provides a succinct introduction to cancer immunotherapy. It highlights how harnessing the immune system is transforming cancer treatment and bringing new hope for cures.

The video is part of a series that explains the five most common immunotherapy approaches currently in use:

• Monoclonal Antibodies: Laboratory-produced molecules designed to target specific cancer cells, helping the immune system recognize and destroy them.
• Checkpoint Inhibitors: Drugs that block proteins used by cancer cells to evade immune attack, thereby reactivating immune responses against tumors.
• Cancer Vaccines: Treatments that stimulate the immune system to recognize and attack cancer-specific antigens.
• Adoptive Cell Therapy: A method involving the extraction, enhancement, and reinfusion of a patient’s own immune cells to better fight cancer.
• Oncolytic Viruses: Viruses engineered to selectively infect and kill cancer cells while stimulating an immune response.

While the video is brief and introductory, it serves as a helpful bridge between simple overviews and more detailed clinical protocols. It emphasizes the progress made over decades of research and the availability of FDA-approved immunotherapies for various cancers.

Source Information

This content is from a 2015 video by the Cancer Research Institute, a leading organization dedicated to advancing cancer immunotherapy research for over 60 years. The video is narrated by Dr. Jill O'Donnell-Tormey and is part of a series designed to educate patients and caregivers. For more detailed information and resources, including clinical trial opportunities, visit Cancer Research Institute and their patient community at theanswertoocancer.org.

Rutgers Cancer Institute explains immunotherapy as treatment that helps the immune system identify and attack cancer cells. The page and embedded videos cover major immunotherapy categories, including immune checkpoint inhibitors, engineered T-cell therapy, monoclonal antibodies, cancer treatment vaccines, and immune system modulators.